Effectiveness of mycophenolate/voclosporin combination therapy in lupus nephritis

Comment on: “Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial” (Lancet. 2021; doi: 10.1016/S0140-6736(21)00578-X.) Commented by: George Bertsias, Rheumatology Clinic, University of Crete School of Medicine, Greece Despite advances in the management of lupus nephritis, still a sizeable number of patients will fail … Read more

A gene-centric pathway stratification of SLE patients

Comment on: “Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing” (Ann Rheum Dis. 2021; 80(1):109-117. doi: 10.1136/annrheumdis-2020-218636) Commented by: George Bertsias, Rheumatology Clinic, University of Crete School of Medicine, Greece SLE is characterized by remarkable clinical and immunological heterogeneity, which likely reflects the variety and complexity of the underlying molecular … Read more